Adjusting to Life After ASCT - HealthTree for Multiple Myeloma
[logo] HealthTree Foundation
search person
chevron_left The Complete Patient’s Guide to Autologous Stem Cell Transplant (ASCT)

Adjusting to Life After ASCT

Last updated on: 3/25/2025

Recovering from an autologous stem cell transplant (ASCT) is a gradual process that may take a year or longer. While your primary goal is to regain strength and adjust to life post-transplant, you may also face emotional, social, and physical challenges along the way.

“How do I measure success? I ask myself this often. I admit I didn’t rush into having a stem cell transplant; I was determined to not go this route. What changed my mind? When I started to think of an ASCT as a protocol or ‘another [myeloma] treatment.’ Success was not a guarantee, but what was for certain was my attitude walking into the ASCT. Once I embraced this, the transplant made sense as the next step to getting my multiple myeloma under control.”

– Mary Sage

Each patient’s long-term recovery journey is different—some find new meaning in life, while others struggle with the disruptions and adjustments required. Whether your recovery is smooth or difficult, most patients learn to adapt and maintain a hopeful outlook.

  • Emotional and Mental Health – You may feel a sense of loss, discouragement, or even grief for the life you had before treatment. Therapy, counseling, or support groups can be valuable in helping you adjust.
  • Changes in Relationships – Your experience may have altered your relationships with family and friends. Open communication can help re-establish mutual understanding and support.
  • Physical Recovery – Regaining full strength and fitness takes time. A gradual return to work, school, or daily activities is recommended.
  • Medical Follow-Ups – Regular oncology visits, bloodwork, and imaging will monitor your recovery and determine if maintenance therapy is needed.