Tocilizumab (toci) is an anti-il-6 antibody designed to interrupt the inflammatory process that causes cytokine release syndrome.
After testing what effect preventative toci could have against CRS, Ellen Marin, PA-C, and her research team at Winship Cancer Institute at Emory University Hospital reported on their findings at the American Society of Hematology (ASH) 2023. Teclistamab was the bispecific antibody used in this study.
Current investigations are focused on identifying earlier which patients are at a higher risk of experiencing CRS so it can be prevented. Gathering real-world data is important for figuring out the best strategies to prevent CRS.
There is also emerging information about wearable technology devices that can detect CRS early within patients. While expensive, these could be a great option in preventing serious complications when myeloma patients receive their bispecific antibody therapy at home.