How Effective is Venetoclax After a BTK Inhibitor or Chemotherapy? - HealthTree for Chronic Lymphocytic Leukemia
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How Effective is Venetoclax After a BTK Inhibitor or Chemotherapy?

Last updated on: 1/6/2025

Venetoclax After a BTK Inhibitor 

If you take venetoclax after a BTK inhibitor, you might wonder how well venetoclax will work for you. Studies have shown the following data: 

  • You have an 84.1% chance that you'll achieve a response (CLL is partially or fully reduced)
  • The average progression-free survival (PFS) you can expect is 3.6 years. Average PFS refers to the amount of time the cancer has not progressed and/or patients have been alive since the start of treatment

Venetoclax After Chemotherapy and a BTK Inhibitor 

If you have received chemotherapy as your first treatment, followed by a covalent BTK inhibitor, then receive treatment with venetoclax, studies show the following: 

  • You have a 78.3% chance that you'll achieve a response (CLL is partially or fully reduced)
  • The average PFS is 3.7 years

Despite previously being treated with a BTK inhibitor or chemotherapy, patients who receive venetoclax have high response rates. If you are interested in taking venetoclax after a BTK inhibitor or chemotherapy, reach out to your CLL specialist to evaluate this treatment option.