
In a recent press release, Amgen announced results of their Phase 3 CLARION trial which was a head-to-head comparison of Kyprolis/melphalan/prednisone vs. Velcade/melphalan/prednisone for patients who were not eligible for autologous stem cell transplant. Patients had similar progression free survival (22.3 months on KMP and 22.1 months on VMP). The CLARION results for the study were disappointing for Amgen, but few patients use the melphalan combinations, particularly in the US.

about the author
Jennifer Ahlstrom
Myeloma survivor, patient advocate, wife, mom of 6. Believer that patients can help accelerate a cure by weighing in and participating in clinical research. Founder of HealthTree Foundation (formerly Myeloma Crowd).
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