Can non-chemotherapy approaches improve myeloma patients' immune systems to improve quality of life or even lengthen remission for myeloma patients? This clinical trial is hoping to learn more testing several types of interventions like strength training, intermittent fasting and the use of beta-blockers.
Physical activity, nutritional interventions, and the use of medications to treat tremors and anxiety (like Propanolol), which don't involve chemotherapy, may be able to improve immune function and quality of life in people with multiple myeloma without the added side effects that come with chemotherapy.
By studying these non-chemotherapy interventions, researchers can determine if they are effective and safe options for patients with myeloma and provide additional treatment options that can improve their quality of life and immune function.
The main goal of the study is to find out if non-chemotherapeutic interventions, like propranolol, can improve the immune system and quality of life in people with multiple myeloma and to learn more about how these interventions affect the treatment of multiple myeloma.
The trial will be divided into several groups, or "modules."
The trial also includes two sub-studies.
Patients with smoldering myeloma or multiple myeloma that have no comorbidities, symptoms of multiple myeloma, or treatment side effects that would make participating in the study unsafe and an Eastern Cooperative Oncology Group (ECOG) Performance Status of 0-2, depending on the experimental group they are in.
For more information about the inclusion and exclusion criteria, click here.
This study is open at the Roswell Park Cancer Institute in Buffalo, New York.
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about the author
Arturo Hurtado is an International Medical Graduate who Joined HealthTree in 2020 as part of The Patient Experience team. He helps patients understand their disease panorama and navigate their myeloma through the tools and resources that HealthTree provides. He is an enthusiastic photographer, tech nerd, and aspiring food explorer who loves to travel and find new exciting experiences.
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