Several clinical trials are taking place right now at trying to prevent smoldering myeloma from progressing to active myeloma. One clinical trial open at Emory University is using a drug called iberdomide which has immunomodulating and cancer killing activities. This means that it helps to induce myeloma cell death and at the same time it helps the immune system to be stronger (by activating T-lymphocytes).
The iberdomide clinical trial is a Phase II study including 68 participants that aims to evaluate the effects of iberdomide when given alone or in combination with dexamethasone in treating intermediate or high-risk smoldering multiple myeloma patients. Immunotherapy with iberdomide may induce changes in body's immune system and may interfere with the ability of cancer cells to grow and spread.
The study is broken into two groups where one group of patients will receive iberdomide and dexamethasone (Arm A); while the other group will receive iberdomide alone (Arm B). Patients can join the study if they have/are:
The study will review the overall response rate (ORR) comparing the two arms. It will also review:
Patients can join if they have intermediate or high-risk smoldering multiple myeloma that includes at least one of the following risk factors:
If you need assistance finding or joining clinical trials, please contact our Patient Navigator support team at 1-800-709-1113 or at firstname.lastname@example.org.
Did you know you can find more clinical trials in HealthTree Cure Hub?
All you have to do is create your free account at healthtree.org, complete your profile and find treatment options (including clinical trials) that meet your specific needs.
Remember that the only way to advance is to investigate as much as possible. This is the reason why enrolling into clinical trials is our best shot to find a cure.
about the author
Eduardo Franco is an International Medical Graduate who Joined HealthTree in 2020 as part of The Patient Experience team. He reads the patient’s medical records and compares them with the information reported by patients on Healthtree so we can have the most exact information on our platform. He is a martial arts practitioner, drummer and avid reader.