How it Works

In multiple myeloma, osteoclasts (cells that break down bone) are overactive, so more bone is destroyed faster than new bone can be created. Osteoclasts can cause lesions that weaken the bone and lead to complications. Some of the complications resulting from this bone breakdown are bone pain, fractures, and, less commonly, hypercalcemia (increased levels of calcium in the blood). Zometa slows osteoclast activity.

How it’s Administered

A healthcare provider will administer this injection by infusion into a vein (>15 minutes).

Who Should Take Zometa

Zometa is currently approved for:

• Patients who have high calcium levels in the blood 
• Patients with multiple myeloma or other types of cancer have affected the bones

Who Shouldn’t Take Zometa

• Patients with hypersensitivity to Zometa
• Patients with severe kidney problems 
• Patients who are pregnant 
• Patients with low calcium blood levels

The Most Common Side Effects of Taking Zometa Include: 

• Bone pain
• Nausea 
• Mild fever
• Fatigue
• Anemia
• Vomiting
• Constipation
• Flu-like symptoms

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