Understanding Multiple Myeloma Clinical Trials: Observational vs. Interventional Studies with Real-World Examples
Event Description
Join our Black Myeloma Health webinar for an in-depth discussion on the differences between observational and interventional clinical trials, and how they impact multiple myeloma research. We'll explore key studies advancing our understanding of multiple myeloma, including the PROMISE, HALO, and immunoPRISM Studies. Learn how each study works, the benefits of participation, and how clinical trials contribute to improving outcomes in the myeloma community.
Event Highlights
Screening and Early Detection of Myeloma
Understanding Precursor Conditions
Observational (or Screening) Trial v.s. Interventional Trial
Promise Study for High-Risk Individuals
Mass Spectrometry for Early Detection
Return of Results and Follow-Up
Immuno-PRISM Trial for High-Risk Smoldering Myeloma
Questions & Answers
Schedule & Agenda
Valarie introduces the agenda of the event and our featured speakers Dr. Irene Ghobrial.
Valarie introduces the agenda of the event and our featured speakers Dr. Irene Ghobrial.
Dr. Irene Ghobrial shares about how clinical trials contribute to improving outcomes in the myeloma community.
Dr. Irene Ghobrial shares about how clinical trials contribute to improving outcomes in the myeloma community.
Type your questions in the chat and we will answer them!
Type your questions in the chat and we will answer them!
Speakers & Moderators
Valarie embarked on her myeloma journey back in 2015, and ever since she's been on a mission. As a resilient myeloma thriver, her passion lies in not just navigating her own path but also in illuminating the journey for others. With a steadfast commitment to understanding the intricacies of the disease, she champions education, shedding light on health inequities that often lurk in the shadows. Driven by a profound belief in fairness, Valarie tirelessly advocates for equitable access to top-tier healthcare, clinical trials, and tailored treatments. Her journey as a beacon of knowledge and support began when she assumed the role of a support group leader. Today, she continues to extend her hand as a myeloma coach, mentor angel, and the guiding force behind the Black Myeloma Health Community. Valarie's voice echoes far and wide as she fearlessly confronts the disparities faced by myeloma patients. Through collaborative efforts with healthcare providers, she strives to forge pathways to solutions, ensuring that every individual receives the care they deserve. Join Valarie on her journey of empowerment and advocacy as she lights the way toward a brighter, more equitable future in myeloma care.
Irene Ghobrial, MD, is a Professor at the Dana-Farber Cancer Institute (DFCI), Harvard Medical School and an associate member of the Broad Institute. She is Director of the Michele & Stephen Kirsch Laboratory and co-director of the Center for Prevention of Progression (CPOP) at DFCI. Additionally, she is the co-leader of the Blood Cancer Research Partnership (BCRP), a consortium for innovative clinical trials of community oncology sites coordinated by DFCI. Dr. Ghobrial’s research focuses on understanding mechanisms of tumor progression from early precursor conditions such as monoclonal gammopathy of undetermined significance (MGUS) and smoldering disease to symptomatic multiple myeloma and Waldenström Macroglobulinemia. She specifically focuses on the role of malignant bone marrow niche in regulating disease progression. She is interested in the development of new molecular/genomic markers that predict progression in precursor conditions which can identify patients who should be eligible for therapeutic interventions to prevent progression or potentially cure the disease at the early stages before clonal evolution occurs. She has authored or co-authored more than 250 publications and book chapters. She has received multiple awards including membership in the American Society of Clinical Investigation, the Robert A. Kyle Award for Research in Waldenström Macroglobulinemia, and the Mentor of the Year Award at DFCI in 2014. Dr. Ghobrial completed her hematology/oncology subspecialty training at the Mayo Clinic College of Medicine in Rochester, MN and internal medicine training at Wayne State University in Detroit, MI. She earned her medical degree from the Cairo School of Medicine in Egypt.
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