Multiple myeloma patients pick up more of the CD28 - HealthTree for Multiple Myeloma
[logo] HealthTree Foundation
more_vert
close
person Sign In / Create Account

Multiple myeloma patients pick up more of the CD28 protein as they relapse. A new solution for this relapsed/refractory target and for 14;16 patients specifically with Dr. Carmen Baldino, PhD and Dr. Kelvin Lee, MD

Multiple myeloma patients pick up more of the CD28 protein as they relapse. A new solution for this relapsed/refractory target and for 14;16 patients specifically with Dr. Carmen Baldino, PhD and Dr. Kelvin Lee, MD image

Multiple myeloma patients pick up more of the CD28 protein as they relapse. A new solution for this relapsed/refractory target and for 14;16 patients specifically with Dr. Carmen Baldino, PhD and Dr. Kelvin Lee, MD

Podcast
event May 13, 2015 / 11:00AM MDT
link icon facebook logo X logo linkedin logo reddit logo email icon

Event Description

 CD28 is a protein is found on multiple myeloma cells and is present in 25% of newly diagnosed patients, in 50% of patients at first relapse, in 80-90% of patients at second relapse and in 100% of plasma cell leukemia patients. Drs. Baldino and Lee are using this significant observation to develop and test a new PIM2 kinase inhibitor called JP-11646 is a PIM2 kinase inhibitor to influence this protein. The new drug also affects the MAF gene - a gene that is changed somewhat in all myeloma patients and is especially affected in patients with the 14;16 translocation. The connection between MAF, PIM2 and CD28 are not totally understood, but this new drug is now being tested for patients with this translocation and patients with late-stage disease.  Dr. Carmen Baldino and Dr. Lee describe the double strategy to bring patients back to a state where they are sensitive to chemo again and also to kill myeloma cells outright. Jasco Pharmaceuticals has taken care to find and develop this new treatment that could address the big issue of very aggressive chemo-resistant myeloma.   The Myeloma Crowd Radio Show with Dr. Carmen Baldino, PhD and Dr. Kelvin Lee, MD

Schedule & Agenda

Event panelist Dr. Carmen Baldino, PhD and Dr. Kelvin Lee, MD and Jenny Ahlstrom
11:00 AM
Discussion Jenny Ahlstrom
Dr. Carmen Baldino, PhD and Dr. Kelvin Lee, MD and Jenny Ahlstrom

Speakers & Moderators

The panelist Jennifer Ahlstrom
Jennifer Ahlstrom

Myeloma survivor, patient advocate, wife, mom of 6. Believer that patients can help accelerate a cure by weighing in and participating in clinical research. Founder of the HealthTree Foundation.

Read Bio

Have Any Questions?

Thank you for your interest in the event. If you have any questions, we would love to help!

Feel free to give us a call or send us a message below.

support

Get In Touch With Us

phone

1-800-709-1113

email

Support@healthtree.org

Thanks to our sponsors:
Johnson and Johnson logo
Sanofi logo
Pfizer logo
GSK logo
Regeneron logo
All HealthTree resources available anywhere, anytime
Download our App
Download iOS App Download Android App
iphone app mockup
newsletter icon

Get the Latest Multiple Myeloma Updates, Delivered to You.

By subscribing to the HealthTree newsletter, you'll receive the latest research, treatment updates, and expert insights to help you navigate your health.