Often, cancer treatments can cause side effects that affect quality of life. Your care team wants to help you manage these side effects and improve your day-to-day life. Always talk to your care team if you are experiencing a side effect that is affecting your daily life.

Capillary leak syndrome during BPDCN treatment

Capillary leak syndrome is a serious side effect associated with tagraxofusp (Elzonris).  It occurs when plasma, the liquid component of blood, leaks into muscles, tissues, and organs.  

This side effect typically occurs during the first treatment cycle and is less likely to occur in subsequent treatment cycles. Healthcare providers treat capillary leak syndrome with the use of glucocorticoids, albumin infusions, and careful management of hydration status.

Peripheral edema during BPDCN treatment

Peripheral edema is commonly reported in patients treated with PVEK. Peripheral edema refers to the swelling of the body, typically in legs, ankles, and feet, caused by a build up of fluid. If you develop edema, your provider may modify your medication or prescribe a diuretic to reduce the amount of swelling. 

Side effects of chemotherapy during BPDCN treatment

Common side effects reported with the use of chemotherapy for BPDCN include: 

• Nausea
• Vomiting 
• Diarrhea 
• Hair Loss
• loss of appetite 
• Fatigue
• Fever
• Mouth sores 
• Pain
• Constipation 
• Easy bruising 
• Bleeding
• Increased risk of infection

Finding help with HealthTree's Side Effects Solutions tool

Find solutions for side effects on HealthTree’s Side Effects Solutions Page.  Here you will discover what has and hasn’t worked for other people with blood cancer.  You can also support fellow patients by adding solutions you’ve found helpful.  

Please note that the information provided on the Side Effects Solutions page is not intended to be used as a substitute for medical advice or discussions with your healthcare provider. 

HealthTree's Side Effect Solutions Tool