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Introduction

Last updated on: 2/19/2026

Welcome! This guide was developed as a resource to help people with blastic plasmacytoid dendritic cell neoplasm (BPDCN) and their caregivers better understand and navigate the disease.

This guide provides an overview of BPDCN. It includes signs and symptoms, common genetic mutations associated with BPDCN, and how BPDCN is diagnosed. It explains the available treatment options, offers practical tips on managing life with BPDCN, shares expert medical commentary, and highlights resources to help people with BPDCN and their loved ones. 

To navigate this comprehensive guide, use the side panel to move through the different sections. You can also use the left and right arrows on each page to browse the information section. If you are viewing the guide on a mobile device, click the horizontal lines icon at the top right of your screen to find the navigation panel.  

Our understanding of BPDCN continues to evolve as more information becomes available through research. While we strive to keep the guide updated with the latest information, some data may not reflect all recent developments. We’ve incorporated timestamps that reflect the last time information was updated.

This guide is intended for informational purposes only and should not replace conversations with your medical team. Always discuss your questions or concerns about your treatment plan with a specialist. 

Authors: Bethany Howell, Leslie Fannon Zhang

Medically reviewed by Dr. Marlise Luskin, MD, MSCE

Thank you to our sponsor, AbbVie.