Robert Z. Orlowski, MD
MD Anderson Cancer Center
Interview Date: January 5, 2018
Much is happening in the world of myeloma. Where are we headed in 2018? Dr. Robert Z. Orlowski of the MD Anderson Cancer Center joins us to share the latest. He reviews a variety of treatment options for smoldering myeloma, emphasizes the expanded use of daratumumab for all patient settings, reminds us that cyclophosphamide (an older drug) can still be used effectively and reviews the importance of maintenance therapy. He notes the progress of minimal residual disease MRD) testing. He shares the up-and-coming immunotherapies like isatuximab, the new Glaxo-Smith-Klein antibody and the use of venetoclax for patients with the 11;14 translocation.
Most importantly he shares the importance of being treated by a myeloma specialist. Newly diagnosed patients who see a myeloma specialist can have 40% better overall survival. And in general, those who are treated by myeloma specialists can live 22% longer than those who don't. To find a myeloma specialist, click here.
Thanks to our episode sponsor, Takeda Oncology
Robert Z. Orlowski, M.D., Ph.D., is Director of Myeloma, and Professor of Medicine in the Departments of Lymphoma/Myeloma and Experimental Therapeutics, where he is board-certified in medical oncology. Dr. Orlowski earned his doctoral degree in molecular biophysics and biochemistry from Yale University and his medical degree from the Yale University School of Medicine. He completed his internship and residency in Internal Medicine at Barnes Hospital at the Washington University in St. Louis School of Medicine. After his fellowships in Hematology and Medical Oncology at John Hopkins Sidney Kimmel Comprehensive Cancer Center, he joined the faculty at University of North Carolina in Chapel Hill. Following that, Dr. Orlowski accepted a position at The University of Texas MD Anderson Cancer Center in 2007 to lead the Myeloma Section in the Department of Lymphoma/Myeloma. His research interests include pathobiology of, novel therapeutic targets and mechanisms of drug resistance in myeloma which are documented in hundreds of scientific articles, book chapters, and presentations at conferences. Dr. Orlowski is an investigator on numerous clinical trials, and appointed Myeloma Committee Chair for SWOG.
Myeloma survivor, patient advocate, wife, mom of 6. Believer that patients can help accelerate a cure by weighing in and participating in clinical research. Founder of the HealthTree Foundation.
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