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Primary Mediastinal B-Cell Lymphoma (PMBCL) is a rare type of non-Hodgkins lymphoma that originates in the mediastinum, the area in the chest between the lungs. The symptoms of PMBCL can vary depending on the size and location of the tumor. However, there are some common signs and symptoms that patients with this condition may experience.

The Most Common Signs and Symptoms of Primary Mediastinal B-Cell Lymphoma include:

  • Cough or shortness of breath: As the tumor grows in the chest, it can press against the lungs or airways, causing respiratory symptoms.
  • Chest pain or discomfort: The tumor can also press against other structures in the chest, leading to pain or discomfort.
  • Swelling in the face, neck, or upper body: This can occur if the tumor is pressing against the superior vena cava, a large vein that carries blood from the upper body to the heart.
  • Unexplained weight loss: Like many cancers, PMBCL can cause a loss of appetite and unexplained weight loss.
  • Fatigue: This is a common symptom of many cancers, including PMBCL. It can be caused by the body's response to the cancer or by the cancer itself.
  • Night sweats or fever: These are known as B symptoms and can be a sign of lymphoma.

Seek Care For Your Primary Mediastinal B-Cell Lymphoma

If you or someone you know is experiencing any of these symptoms, it is important to seek medical attention. While these symptoms can be caused by conditions other than PMBCL, it is important to rule out this serious condition. A healthcare provider can perform a physical examination and order tests, such as imaging studies or a biopsy, to determine the cause of the symptoms. If PMBCL is diagnosed, treatment options can include chemotherapy, radiation therapy, immunotherapy, or a combination of these. The choice of treatment will depend on the stage of the disease, the patient's overall health, and other factors.

If you are experiencing any of these symptoms and want to know what has worked for other blood cancer patients, visit HealthTree's Side Effect Solutions tool. Here you can search for the symptoms you are experiencing and read about what's worked (and what hasn't worked) for patients just like you.

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