DRUG: Methotrexate
DRUG: pralatraxate,
DRUG: Ifosfamide
DRUG: Dexamethasone
DRUG: Etoposide
DRUG: calaspargase pegol
DRUG: cyclophosphamide
DRUG: Doxorubicin
DRUG: Prednisone
DRUG: Brentuximab Vedotin
BIOLOGICAL: CD19/CD22 CAR T-Cells
DRUG: Fludarabine
DRUG: Cyclophosphamide
BIOLOGICAL: 19-28z/IL-18 CAR T cells
DRUG: Calaspargase pegol (S95015)
DRUG: CD22CART Infusion
PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Aspiration
PROCEDURE: Bone Marrow Biopsy
BIOLOGICAL: CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/mem-enriched T-lymphocytes
BIOLOGICAL: Cetuximab
PROCEDURE: Computed Tomography
DRUG: Cyclophosphamide
PROCEDURE: Echocardiography
DRUG: Fludarabine
PROCEDURE: Leukapheresis
PROCEDURE: Magnetic Resonance Imaging
PROCEDURE: Multigated Acquisition Scan
PROCEDURE: Positron Emission Tomography
PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
DRUG: Cyclophosphamide
DRUG: Cyclosporine
BIOLOGICAL: Filgrastim
DRUG: Fludarabine
DRUG: Mycophenolate Mofetil
DRUG: Mycophenolate Sodium
RADIATION: Total-Body Irradiation
DRUG: Treosulfan
PROCEDURE: Bone Marrow Aspiration
PROCEDURE: Bone Marrow Biopsy
PROCEDURE: Echocardiography
PROCEDURE: Biospecimen Collection
PROCEDURE: Computed Tomography
PROCEDURE: Positron Emission Tomography
DRUG: Brentuximab vedotin
RADIATION: Total-Body Irradiation
DRUG: Thiotepa
DRUG: Fludarabine
DRUG: Cyclophosphamide
DRUG: Busulfan
PROCEDURE: Allogeneic Bone Marrow Transplantation
DRUG: Tacrolimus
DRUG: Methotrexate
PROCEDURE: Naive T Cell-Depleted Hematopoietic Stem Cell Transplantation
GENETIC: KUR-502
DRUG: Cyclophosphamide injection
DRUG: Fludarabine Injection
BIOLOGICAL: CD19-CD34t metabolically programmed CAR transduced T-cells
GENETIC: CD19.CAR-aNKT cells
BIOLOGICAL: CD19/CD22-CAR-transduced T cells
DRUG: cyclophosphamide
DRUG: fludarabine
DRUG: Daratumumab / Hyaluronidase Injection
DRUG: Daratumumab / Hyaluronidase Injection
DRUG: Daratumumab / Hyaluronidase Injection
DRUG: Daratumumab / Hyaluronidase Injection
DRUG: Daratumumab
DRUG: Cyclophosphamide
DRUG: Fludarabine
BIOLOGICAL: Mogamulizumab
BIOLOGICAL: Natural Killer Cell Therapy
OTHER: Quality-of-Life Assessment
OTHER: Questionnaire Administration
DEVICE: CliniMACS
BIOLOGICAL: Allogeneic Natural Killer Cell Line NK-92
BIOLOGICAL: Anti-Thymocyte Globulin
DRUG: Busulfan
DRUG: Clofarabine
DRUG: Cyclophosphamide
DRUG: Fludarabine Phosphate
OTHER: Laboratory Biomarker Analysis
DRUG: Melphalan
BIOLOGICAL: Rituximab
RADIATION: Total-Body Irradiation
PROCEDURE: Umbilical Cord Blood Transplantation
BIOLOGICAL: BEAM-201
DRUG: KT-333
DRUG: Dasatinib
DRUG: Methotrexate
DRUG: Prednisone
BIOLOGICAL: Rituximab
DRUG: Venetoclax
BIOLOGICAL: Blinatumomab
PROCEDURE: Bone Marrow Aspiration and Biopsy
PROCEDURE: Lumbar Puncture
PROCEDURE: Biospecimen Collection
DRUG: AKR1C3-activated Prodrug OBI-3424
BIOLOGICAL: Autologous, humanized anti-CD22 CAR T cell therapy (CART22-65s)
BIOLOGICAL: Autologous, humanized anti-CD19 CAR T cell therapy (huCART19)
BIOLOGICAL: SCRI-CAR22v2
GENETIC: ALLO-501A
BIOLOGICAL: ALLO-647
DRUG: Fludarabine
DRUG: Cyclophosphamide
DRUG: Fludarabine
DRUG: Busulfan
DRUG: Melphalan
DRUG: Rituximab
DRUG: Levetiracetam
DRUG: Dasatinib
DRUG: ABBV-101
DRUG: 1A46 Injection
BIOLOGICAL: Rapcabtagene autoleucel single agent
DRUG: Ibrutinib
PROCEDURE: Biopsy
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Biopsy
PROCEDURE: Computed Tomography
DRUG: Cyclophosphamide
PROCEDURE: Positron Emission Tomography
BIOLOGICAL: Recombinant Vesicular Stomatitis Virus-expressing Human Interferon Beta and Sodium-Iodide Symporter
PROCEDURE: Single Photon Emission Computed Tomography
BIOLOGICAL: Cemiplimab
PROCEDURE: Biospecimen Collection
BIOLOGICAL: Blinatumomab
PROCEDURE: Bone Marrow Aspiration and Biopsy
DRUG: Cyclophosphamide
DRUG: Cytarabine
DRUG: Dasatinib
DRUG: Dexamethasone
DRUG: Doxorubicin Hydrochloride
PROCEDURE: Echocardiography
PROCEDURE: Electrocardiography
PROCEDURE: Lumbar Puncture
DRUG: Mesna
DRUG: Methotrexate
PROCEDURE: Multigated Acquisition Scan
DRUG: Ponatinib Hydrochloride
DRUG: Prednisone
DRUG: Vincristine Sulfate
DRUG: Blinatumomab
DEVICE: Current Wearable Heatlth Monitoring System (CWHMS)
BIOLOGICAL: CD19-CAR(Mem) T-cells
DRUG: Cyclophosphamide
DRUG: Fludarabine
DRUG: Mesna
DEVICE: CliniMACS
PROCEDURE: Leukapheresis
BIOLOGICAL: Chimeric Antigen Receptor T-Cell Therapy
DRUG: Cyclophosphamide
DRUG: Fludarabine Phosphate
OTHER: Laboratory Biomarker Analysis
OTHER: Questionnaire Administration
DRUG: CD22CART infusion
DRUG: Tisagenlecleucel
DRUG: etoposide
DRUG: cyclophosphamide
RADIATION: total marrow irradiation
PROCEDURE: allogeneic hematopoietic stem cell transplantation
PROCEDURE: allogeneic bone marrow transplantation
OTHER: Laboratory Biomarker Analysis
DRUG: Venetoclax
DRUG: Vincristine Liposomal
BIOLOGICAL: CTX131
DRUG: Cyclophosphamide
DRUG: Cytarabine
DRUG: Dexamethasone
DRUG: Doxorubicin Hydrochloride
DRUG: Mercaptopurine
DRUG: Methotrexate
DRUG: Nelarabine
DRUG: Pegaspargase
DRUG: Prednisone
DRUG: Venetoclax
DRUG: Vincristine Sulfate
DRUG: DR-01
BIOLOGICAL: WU-CART-007
DRUG: Allogeneic donor-derived T-cells transduced with bivalent lentiviral vector (CD19/CD22-BBz) chimeric antigen receptor (CAR)
DRUG: Treg CD34+HSPC (Orca-T)
DRUG: CD19 Directed CAR T Cell
DRUG: Autologous Anti-CD19 CAR-expressing T Lymphocytes
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Aspiration and Biopsy
DRUG: Cyclophosphamide
DRUG: Fludarabine
PROCEDURE: Leukapheresis
OTHER: Questionnaire Administration
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Biopsy
PROCEDURE: Computed Tomography
DRUG: Cyclophosphamide
DRUG: Doxorubicin Hydrochloride
DRUG: Etoposide
DRUG: Lenalidomide
PROCEDURE: Positron Emission Tomography
DRUG: Prednisone
DRUG: Vincristine Sulfate
![newsletter icon](https://static.healthtree.org/icons/newsletter-icon.png)
Get the latest thought leadership on your Adult T-cell Leukemia / Lymphoma delivered straight to your inbox
Subscribe to the weekly newsletter for news, stories, clinical trial updates, and helpful resources and events with cancer experts.