How Clinical Trial Endpoints Shape Therapy Approvals and What They Mean for You
Understanding Primary and Secondary Endpoints
Understanding Surrogate Endpoints
What are Common Endpoints in Myeloma Clinical Trials?
Progression-Free Survival (PFS)
Overall Response Rate (ORR)
Minimal Residual Disease (MRD)
Patient-Related Outcomes and Real-World Data
Other Clinical Trial Endpoints
How Are Clinical Trial Phases and their Endpoints Related?
Phase I: Safety and Tolerability
Phase II: Efficacy and Dosage
Phase III: Comparison to Standard-of-Care
Phase IV: After-Market Observations
Clinical Trial Design and Other Terminology
Understanding Clinical Trial Design
Why Participate in Clinical Trials?
Why Others Participate In Myeloma Clinical Trials and Research
Questions to Ask Your Doctor