I am enrolled in the Sim0500 trial which is a Trispecific targeting GPRC5D–BCMA–CD3 . It has been giving unbelievable results. My myeloma numbers were normal within 8 days of getting my first injection . It has not been without trials. The skin side effects as well as the taste changes are typical of GPRC5D agents. To me this is a miracle as my myeloma was very aggressive after relapsing in 9 months after my Car-T. I move on now to my six months of treatment. The side effects have lessened but are still there but tolerable. My labs are still good. My PET scan has shown a dramatic decrease in the myeloma lesions but they are still there. I will get my bone marrow biopsy next month. I am hopeful.