What Is Peripheral T-Cell Lymphoma?

Peripheral T-Cell Lymphoma (PTCL) is a type of non-Hodgkin lymphoma that develops in the T-cells, a type of white blood cell that plays a crucial role in the immune system. PTCL is a rare and aggressive form of lymphoma that typically affects adults. It can occur anywhere in the body but is most commonly found in the lymph nodes, skin, gastrointestinal tract, and bone marrow. The symptoms of PTCL can vary widely but often include enlarged lymph nodes, fever, weight loss, and night sweats.

Why do people get Peripheral T-Cell Lymphoma?

The exact cause of Peripheral T-Cell Lymphoma is not known. However, it is believed to be related to mutations in the T-cells that cause them to grow and divide uncontrollably. Certain factors may increase the risk of developing PTCL, including:

• Age- it is more common in adults.
• Gender- it is more common in men.  
• A weakened immune system.
• Certain viral infections- the Epstein-Barr virus and Human T-cell lymphotropic virus type 1 (HTLV-1), have also been associated with an increased risk of PTCL. However, it's important to note that most people with these risk factors do not develop PTCL, and many people who do develop the disease have no known risk factors.

Who gets Peripheral T-Cell Lymphoma?

Approximately 6,000 new cases of PTCL are diagnosed every year in the United States. This cancer accounts for less than 10% of all cases of non-Hodgkin's lymphoma diagnosed in North America and Western Europe. 

Want to Learn More About Peripheral T-Cell Lymphoma?

Keep reading HealthTree for Peripheral T-Cell Lymphoma's 101 pages!

• How Is Peripheral T-Cell Lymphoma Diagnosed?
• How Long Will I Live With Peripheral T-Cell Lymphoma?
• What Are The Signs And Symptoms Of Peripheral T-Cell Lymphoma?
• How Is Peripheral T-Cell Lymphoma Staged And Classified?
• What Are Treatments For Peripheral T-Cell Lymphoma?