How is Large Granular Lymphocytic Leukemia Diagnosed?

Large granular lymphocytic leukemia (LGLL) is diagnosed through a combination of blood tests, bone marrow tests, and imaging tests. These tests help to identify the presence of abnormal lymphocytes and assess the extent of the disease.

Blood Tests:

• Complete Blood Count (CBC): This test measures the amount of different types of cells in the blood. In LGLL, there may be an increase in the number of lymphocytes.
• Flow Cytometry: This test is used to identify the type of cells present in the blood. It can detect abnormal lymphocytes that are characteristic of LGLL.
• Immunophenotyping: This test identifies cells based on the types of proteins they express. It can help to confirm the diagnosis of LGLL.
• Cytogenetic Analysis: This test looks at the chromosomes of the lymphocytes. It can identify any genetic changes that are associated with LGLL.

Bone Marrow Tests:

• Bone Marrow Aspiration and Biopsy: These tests involve taking a small sample of bone marrow from the hip bone. The sample is then examined under a microscope to look for abnormal lymphocytes.
• Cytogenetic Analysis: This test can also be performed on bone marrow samples. It can provide additional information about the genetic changes in the lymphocytes.

Imaging Tests:

• Computed Tomography (CT) Scan: This test uses x-rays to create detailed images of the inside of the body. It can help to identify any enlarged lymph nodes or organs.
• Magnetic Resonance Imaging (MRI): This test uses magnetic fields and radio waves to create detailed images of the body. It can provide more detailed information about the lymph nodes and organs.

A Summary of Diagnosing Large Granular Lymphocytic Leukemia

Diagnosing LGLL involves a combination of blood tests, bone marrow tests, and imaging tests. These tests help to identify the presence of abnormal lymphocytes, assess the extent of the disease, and identify any associated genetic changes. The results of these tests can help to confirm the diagnosis of LGLL and guide treatment decisions.

Want to Learn More About Large Granular Lymphocytic Leukemia?

Keep reading HealthTree for Large Granular Lymphocytic Leukemia's 101 pages!

• What Is Large Granular Lymphocytic Leukemia?
• How Long Will I Live With Large Granular Lymphocytic Leukemia?
• What Are The Signs And Symptoms Of Large Granular Lymphocytic Leukemia?
• How Is Large Granular Lymphocytic Leukemia Staged And Classified?
• What Are Treatments For Large Granular Lymphocytic Leukemia?