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Effect of Plant-based Diet on Cardiometabolic and Inflammatory Parameters in Kidney Transplant Recipients
Description
The goal of this clinical trial is to evaluate cardiometabolic and inflammatory parameters in kidney transplant recipients after transitioning to a plant-based diet (PBD). The main aims of the study are as follows: * To test the feasibility of transiting renal allograft recipients who are \> 3 months post-transplant to a PBD * To study the effect of a PBD on cardiometabolic parameters in kidney transplant recipients * To assess the effect of a PBD on peripheral blood Th17/Treg ratio and systemic inflammation in kidney transplant recipients Participants will be asked to: * Complete a 2-week investigator-designed PBD transition program * Follow a PBD for a minimum of 16 weeks * Consent for blood draws, urine samples, and fecal samples along with physical exams * Complete intermittent food frequency questionnaires and quality of life questionnaires * Periodically meet with investigators and other study participants Researchers will compare baseline measurements with future measurement
Trial Eligibility
Inclusion Criteria: * \> 3 months post-kidney transplant * On style immunosuppressive medication * Without evidence of active infection/ inflammatory conditions * Estimated glomerular filtration rate \> 45ml/min/1.73 m\^2 * English speaking * Reliable internet access Exclusion Criteria: * Acute/ chronic allograft rejection * History of non-compliance * Advance heart failure * Liver disease * Pregnancy * Malignancy * Chronic Infection * Currently following a plant-based diet
Study Info
Organization
George Washington University
Primary Outcome
Th17/ Treg ratio
Interventions
Locations Recruiting
Transplant Institute
United States, District of Columbia, Washington
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