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Dietary Intervention to Improve Kidney Transplant Outcomes


Description

Randomized controlled trial of a curriculum intervention teaching patients to eat a whole-food plant-based dietary pattern versus standard of care in kidney transplant recipients within the first few months of transplantA whole-food plant-based dietary pattern has emerged as fundamental in preventing and treating many of the lifestyle-related diseases of Western medicine, including cardiovascular disease, diabetes, hyperlipidemia, obesity, hypertension, chronic kidney disease and certain cancers. These diseases often occur or recur in the post-transplant population, leading to patient and graft loss. However, dietary education for kidney transplant recipients is not standardized and many patients remain ignorant about optimum healthy dietary practices. These patients are further challenged by the common occurrence of electrolyte derangements that require dietary restrictions. We propose a randomized controlled trial of a dietary intervention that focuses on whole-food plant-based eatin

Trial Eligibility

Inclusion Criteria: * Kidney transplant recipient aged 18 or greater * Post-transplant months 2-12 * eGFR \>= 20 mL/min * Have at least one of the following: 1. Hypertension history (BP \>= 150/90 or on BP medications) 2. Hyperglycemia history (FBG \>= 100 x 2 or on diabetes medications) 3. Overweight (BMI \>= 25) Exclusion Criteria: * Rejection episode before study enrollment * Gastrointestinal feeding tube or requires alternative nutrition * Unable to understand or read English * Unable to attend online classes or complete study questionnaires independently * Already eating a plant-based diet * Unwilling to make dietary changes * Pregnant or breastfeeding * Unable to consent * Blindness * Prisoners

Study Info

Organization

University of California, Davis


Primary Outcome

Cardiometabolic health measures


Outcome Timeframe 1 year

NCTID NCT05449496

Phases NA

Primary Purpose TREATMENT

Start Date 2022-06-27

Completion Date 2024-12-30

Enrollment Target 120

Interventions

BEHAVIORAL Dietary Education Curriculum

Locations Recruiting

UC Davis

United States, California, Sacramento


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