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Enhanced Recovery After Surgery in Living Donor Kidney Transplant Donors


Description

Enhanced recovery after surgery (ERAS) pathways are designed to optimize perioperative management, improving patient outcomes and satisfaction through multimodal techniques. Living kidney transplant donors are typically healthy individuals who undergo laparoscopic nephrectomy. The most significant hindrance to discharge to return to activities of daily living is frequently return of bowel function and postoperative pain. Through a randomized controlled trial design, we will evaluate the effectiveness of implementing an ERAS pathway. We hypothesize that preoperative patient optimization through exercise, carbohydrate loading, and counseling on expectations, in addition to multimodal pain management strategies which limit opioids would allow faster recovery, early bowel function, decreased postoperative pain, increased patient satisfaction and shorter length of stay. The study population will include a total of 42 patients (age 18-80) who are American Society of Anesthesiologists (ASA)

Trial Eligibility

Inclusion Criteria: * All patients undergoing this procedure who consent Exclusion Criteria: * patient refusal, female patients who are pregnant or nursing, patients with allergy to local anesthetic, American Society of Anesthesiology classification greater than 3

Study Info

Organization

Thomas Jefferson University


Primary Outcome

post operative opioid consumption


Outcome Timeframe from time after discharge from PACU to discharge from the hospital (up to 7 days)

NCTID NCT04110080

Phases NA

Primary Purpose TREATMENT

Start Date 2019-09-12

Completion Date 2023-06-12

Enrollment Target 42

Interventions

PROCEDURE multimodal pain management

OTHER goal directed fluid management

OTHER preoperative carbohydrate loading

PROCEDURE Donor nephrectomy

PROCEDURE regional anesthesia

Locations Recruiting

Thomas Jefferson University Hospital

United States, Pennsylvania, Philadelphia


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