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MOSES Lithotripsy Technology Applied to Stone Fragmentation During Ureteroscopy


Description

To determine if the effects of MOSES laser modulation technology can improve the safety and efficiency to laser fragmentation resulting in decreased total laser time, reduced potential for injury to the patient, and total OR time and utilization.MOSES technology was developed by Lumenis Ltd to maximize the lithotripsy potential of high powered lasers. Typically, a holmium laser unit is used to treat kidney a ureteral stones that are too large to remove en block. Laser lithotripsy allows for a large stone to be partitioned into smaller fragments that can be removed with an endoscopic basket device. Holmium technology has existed for more than 20 years, however, low total power (40 watt) and minimal modulations (Joules and Hertz) of the laser energy by the laser units limited the capacity to improve lithotripsy efficiency. With the advent of high power (120 watt) lasers with 4 laser cores and developments in software to modulate the laser energy, many more options have emerged for laser

Trial Eligibility

Inclusion Criteria: * \>18 years of age * Kidney or ureteral stone requiring laser lithotripsy fragmentation Exclusion Criteria: * \< 18 years of age * Infectious, struvite stones. * Atypical collecting system anatomy that prolongs the case (ureteral stricture, malrotated kidney, infundibular stenosis, ureteral duplication)

Study Info

Organization

Indiana University


Primary Outcome

The primary endpoint of interest will be reduction in total laser time


Outcome Timeframe Postoperative day 1

NCTID NCT03995758

Phases NA

Primary Purpose TREATMENT

Start Date 2019-06-06

Completion Date 2024-05-24

Enrollment Target 116

Interventions

DEVICE MOSES

Locations Recruiting

Indiana University Health Physicians Urology

United States, Indiana, Indianapolis


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