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Transversus Abdominis Plane (TAP) Blocks With Ropivacaine Continuous Infusion Catheters vs Single Dose Liposomal Bupivicaine: A Prospective Randomized Control Trial for Pain Control After Renal Transplant Surgery
Description
This study is a comparison of the analgesic efficacy of transversus abdominis plane (TAP) blocks with ropivacaine bolus plus continuous ropivacaine infusion via catheters versus single shot TAP blocks with liposomal bupivacaine.This study is a comparison of the analgesic efficacy of TAP blocks provided by ropivacaine bolus plus continuous ropivacaine infusion via catheters versus single shot TAP blocks with liposomal bupivacaine. In the Liposomal Bupivacaine group, TAP block will be performed using ultrasound guidance. 12ml of 0,25% plain bupivacaine will be used for skin infiltration and to open up the TAP. Liposomal Bupivacaine 266 mg (1.3% in 20 ml) will be diluted to 40 ml volume with 20 ml of preservative free normal saline. 20 ml (133mg) of liposomal bupivicaine will then be injected into the TAP. For those randomized to the TAP catheter group, ultrasound guidance will be used for TAP block and 5 mls 1% lidocaine will be used for skin infiltration. A peripheral nerve catheter w
Trial Eligibility
Inclusion Criteria: * Patients ages 18 years or older * Renal Transplant Recipients Exclusion Criteria: * Patients less than 18 years of age * Pregnant Women * Prisoners * Opioid Tolerant Patients taking more than 30 mg/day of oral morphine equivalent analgesia * Patients on Systemic anti coagulation * Patients unable to provide consent * Hypersensitivity to amide-type local anesthetic or any component of the drug formula
Study Info
Organization
University of California, Davis
Primary Outcome
Difference in Total Opioid Consumption
Interventions
Locations Recruiting
University of California Davis
United States, California, Sacramento
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