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An Early Real-Time Electronic Health Record Risk Algorithm for the Prevention and Treatment of Acute Kidney Injury: A Randomized Trial of an Early Standardized, Personalized Nephrology Intervention


Description

This is a single center randomized trial that seeks to determine if the use of an automated real-time electronic medical record Acute Kidney Injury (AKI) risk score can improve patient outcomes through the use of an early standardized nephrology focused intervention.

Trial Eligibility

Inclusion Criteria: 1. Age \>18 years old 2. Initial ESTOP AKI score ≥0.01 within the last 8 hours. Exclusion Criteria: 1. Voluntary refusal or missing written consent of the patient / legal representative. 2. Patients with a known history of end-stage renal disease on dialysis (including renal transplantation). 3. Patients without a measured serum creatinine value during their inpatient stay. 4. Patients with a creatinine \>4.0 mg/dl at the time of admission or available in the electronic health record (EHR) from the last 6 months. 5. Patients with prior episode of Kidney Disease Improving Global Outcomes (KDIGO) defined AKI during this same hospitalization- regardless of ESTOP AKI score. 6. Patients with prior renal consultation during their admission.

Study Info

Organization

University of Chicago


Primary Outcome

Peak change in milligrams per deciliter (mg/dL) in serum creatinine (SCr) level over a 7-day interval


Outcome Timeframe 7-day interval

NCTID NCT03590028

Phases NA

Primary Purpose TREATMENT

Start Date 2018-10-01

Completion Date 2025-06-01

Enrollment Target 180

Interventions

OTHER Early Nephrology Consult (ENC)

OTHER Standard of Care (SOC)

Locations Recruiting

University of Chicago Medical Center

United States, Illinois, Chicago


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