Hello Everyone. I have been SMM since 06/2020. My Doctor is at UT Southwestern and I like her. My numbers seem to be getting worse as my lamba free light chain is at 1689, my protein in a 24 hour specimen is over 400. My plasma is at 30% she to me I was a 20/2/20. I ask here if there was any trials that could help to possible prevent this from becoming active and she keeps telling me no because she said that the meds will make me sick and I might not go active for another 18 months so there is no need to make you fill ill if I don't need to too. I see her every 3 months for blood work and have pet scan every 6 months to make sure no lesions have formed. Should I ask for a second opinion or just let her lead? To be honest this is my third bought with cancer. I have over came kidney cancer and lung cancer. This waiting is killing me. Thank you in advance for your thoughts and advice. Chuck