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Using Cevostamab Consolidation After CAR-T to Improve Outcomes | Adam Cohen, MD | #IMS25 #myeloma

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• September 23, 2025

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Video thumbnail: Using Cevostamab Consolidation After CAR-T to Improve Outcomes | Adam Cohen, MD | #IMS25 #myeloma
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Using Cevostamab Consolidation After CAR-T to Improve Outcomes | Adam Cohen, MD | #IMS25 #myeloma
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In this HealthTree video, Dr. Adam Cohen discusses the Phase 2 STEM trial, which evaluates the safety and efficacy of cevostamab consolidation therapy following BCMA-directed CAR T-cell therapy in patients with heavily pretreated relapsed/refractory multiple myeloma.
Cevostamab, a bispecific antibody targeting FcRH5 and CD3, aims to enhance T-cell engagement against myeloma cells, potentially improving outcomes in this challenging patient population.

Presented at the 22nd International Myeloma Society Annual Meeting, the STEM trial's findings suggest that fixed-duration cevostamab consolidation is feasible and well-tolerated, with promising response rates.

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IMS 2025 - International Myeloma Society Myeloma News Coverage
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https://youtu.be/ndvHWi2H0BA
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2025_09_19 Adam Cohen.mp4
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