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Video

What is the best setting to use NK cell therapy?

Posted by
HealthTree Logo HealthTree
• November 30, 2022

Description

Learn about the best setting to use natural killer cell therapy in this HealthTree University lesson by a cancer specialist.

On this video

Healthtree contact Nina Shah, MD, Specialist

Nina Shah, MD, Specialist

UCSF Helen Diller Family Comprehensive Cancer Center

Transcript

What is the best setting to use NK cell therapy? I think the NK cells have potential to be used in all parts of multiple myeloma, depending on how easy they are to produce. It's always balancing the easiness with the potential for effectiveness and the potential for side effects, right? So if we were thinking about a smoldering myeloma patient and we wanted to use an antibody and we used an effective NK cell with the antibody, you could think about giving a patient four to six cycles of that or a couple of doses with one or two infusions of NK cells and having that be really effective to control their myeloma clone for years and years. That's one place. In the relast refractory place, which is totally the other part of it, you could see how this might rescue something like deritumumab, which the patient may have failed in the past or a distant past and make it work better. And another option, again, for patients to have disease control and then maybe go on to a more effective clinical trial, or maybe this would eradicate the NK clone if it does work on more than one protein and there's more than one antibody that's used.

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