Cytokine Release Syndrome (CRS) After CAR-T: Caregiver Warning Signs

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Cytokine release syndrome (CRS) is a potentially serious side effect of CAR-T cell therapy, and caregivers play an important role in spotting it early. In this HealthTree video, we explain what CRS is, when it is most likely to occur (typically the first 14 days), the early warning signs, and the equipment to have at home: a thermometer, blood pressure cuff, and pulse oximeter. You'll also learn what to do for a fever of 100.4°F (38°C) or higher, what to do after hours, how CRS is graded, and how to prepare at home.

Part of HealthTree University's Caring with Confidence: A Practical Guide for CAR-T Caregivers course.

Timestamps:

0:00 Introduction

0:24 What is cytokine release syndrome (CRS)?

1:22 When CRS is most likely to occur

2:33 Early warning signs of CRS

3:46 Equipment to have at home

5:13 How the medical team monitors for CRS

6:05 What to do if there is a fever

7:23 What to do after hours

8:28 CRS severity grades 1 to 4

9:47 Preparing to monitor at home

11:45 The one thing to remember

This video is for educational purposes only and is not medical advice. Always follow your CAR-T care team's instructions.

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