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Relapsed and Refractory MM Treatment
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1. What is relapsed myeloma and refractory myeloma?
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2. What is progressive disease? Is it the same as relapse?
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3. What is a Biochemical vs Clinical Relapse?
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4. What are the cycles of relapse and remission in myeloma?
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5. Why do drugs stop working?
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6. Do individuals become refractory to a given drug or an entire class of drugs?
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7. What testing should be done at relapse? What is restaging?
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8. What are the goals of treatment at relapse?
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9. With relapsed myeloma, when should you modify current therapy change dosage?
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10. What are the NCCN Treatment Guidelines? What strategy should be used in selecting a therapy?
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11. Why is it important to be consulting with a myeloma specialist at relapse?
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12. What treatments are available for first relapse?
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13. What treatments should be considered in bortezomib/velcade refractory patients at first relapse?
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14. What are some possible monoclonal antibodies and MAB combinations to consider at first relapse?
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15. What are some newer therapies with different mechanisms of action to consider at first relapse?
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16. What does it mean to be triple class refractory?
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17. Is there a role for transplant if not used upfront or a second transplant at first relapse?
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18. What is the role of genomics at relapse?
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19. Are there any targeted approaches for specific genetic subsets that patients should ask about?
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20. How do you decide on an appropriate treatment at relapse with so many to choose from?
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21. When should a patient consider a clinical trial in relapse?
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22. With so many options available, at what point should a patient consider getting a second opinion?
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23. What FDA approved treatments are available treatments for patients with RRMM with received two or more prior lines of therapy?
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24. What is meant by t-cell redirecting therapy?
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25. Where should CAR T cell therapy be positioned in RRMM approved and trials?
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26. Where should bispecific antibodies be positioned in RRMM?
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27. What factors should be considered when choosing between a CAR T cell therapy and a bispecific antibody therapy?
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28. What is a BCMA-Directed Therapy? What are Some FDA Approved BCMA Directed Therapies?
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29. Is There a Role for Conventional Chemotherapy in the treatment of Relapsed and Refractory Myeloma?
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30. Will an Allogeneic Transplant ever be Considered at Relapse?
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31. What are Some Promising Investigational Agents and Novel Therapies for Relapsed/Refractory Patients?
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32. What is the Role of Supportive Care throughout Relapsed and Refractory Myeloma Management?
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33. What is Bone Strengthening Therapy?
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34. What are Some Tips for Coping with the Fear of Relapse?
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35. What are the Unmet Needs and Challenges in the Relapsed/Refractory Myeloma setting?
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36. How can HealthTree help with assessing treatment options at relapse?
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37. What is Off-label Use of a Drug?
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38. (Guest Lecture): Immunotherapies | Experts Discuss Relapsed/Refractory Myeloma, Amyloidosis
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38. What is Considered a Line of Therapy?
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39. (Guest Lecture): Relapsed Refractory Multiple Myeloma - Krina Patel, MD, MSc | RT Irvine, CA Nov 5, 2022
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40. (Guest Lecture): Amyloidosis | Experts Discuss Relapsed/Refractory Myeloma, Amyloidosis
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41. (Guest Lecture) When and How you Become Refractory to a Drug and How to Find the Best Next Treatment
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42. (Guest Lecture): Emerging Treatments | Experts Discuss Relapsed/Refractory Myeloma, Amyloidosis
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43. (Guest Lecture): September 2023 - Personalizing Options for Relapse/Refractory Patients
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44. (Guest Lecture): October 2023 - Personalizing Therapy for Each Relapsed/Refractory Myeloma Patient
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45. (Guest Lecture): March 2024 - The Bounty of Treatments for Early Relapsed Myeloma
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46. (Guest Lecture): March 2024 - Exploring the Myeloma Toolbox
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What is relapsed myeloma and refractory myeloma?
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