
The Latest in Amyloidosis Care and Research with Morie Gertz, MD, Mayo Clinic
Dr. Morie Gertz joins the HealthTree Podcast for Multiple Myeloma to share the challenges, treatments and futures of AL amyloidosis. He shares common treatments used in AL amyloidosis. He also reviews treatment questions now being studied in clinical trials, such as if anti-amyloid treatments can break up the damaging proteins, daratumumab use in amyloidosis, stem cell transplant in amyloidosis and a host of t-cell therapy clinical trials now opening in amyloidosis.
He also shares an invitation for patients to join his amyloidosis survey to better understand patient experiences getting their diagnosis. What symptoms led you to an amyloidosis?
Join Dr. Gertz and many other myeloma specialists complete this important research project.
Amyloidosis clinical trial topics discussed in the show include:
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CAEL101-203: A PHASE 2, OPEN-LABEL, MULTICENTER DOSE SELECTION STUDY TO EVALUATE THE SAFETY AND TOLERABILITY OF CAEL-101 IN PATIENTS WITH AL AMYLOIDOSIS (targeting the amyloid proteins)
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A PHASE 3, RANDOMIZED, MULTICENTER, DOUBLE-BLIND, PLACEBO-CONTROLLED, EFFICACY AND SAFETY STUDY OF BIRTAMIMAB PLUS STANDARD OF CARE VS. PLACEBO PLUS STANDARD OF CARE IN MAYO STAGE IV SUBJECTS WITH LIGHT CHAIN (AL) AMYLOIDOSIS (targeting the amyloid proteins)
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A PHASE I-II TRIAL OF DARATUMUMAB FOR THE TREATMENT OF PATIENTS WITH AL AMYLOIDOSIS
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PHASE 1B DOSE EXPANSION STUDY OF NXC-201 FOR THE TREATMENT OF PATIENTS WITH RELAPSED OR REFRACTORY AL AMYLOIDOSIS (CAR T Study)

Jennifer Ahlstrom
Myeloma survivor, patient advocate, wife, mom of 6. Believer that patients can help accelerate a cure by weighing in and participating in clinical research. Founder of the HealthTree Foundation.

Morie Gertz, MD, MACP
Morie Gertz, MD, MACP, is the Roland Seidler, Jr. Professor of the Art of Medicine and Chair of the Department of Medicine at the Mayo Clinic in Rochester, MN. He is board certified in Internal Medicine, Hematology and Medical Oncology. Dr. Gertz has also served as Treasurer of the International Myeloma Society and President of Mayo Staff Officers and Councilors. He was the Chair of the Mayo Personnel Committee. Currently he serves on the American Society of Hematology Training Program Committee and the American Board of Internal Medicine Hematology Board Exam Committee. Dr. Gertz has been recognized with the 2014 Jan Waldenström Medal for Medical and Scientific Achievements in Waldenström Macroglobulinemia and is a Mayo Distinguished Clinician. He has been recognized for his contributions in amyloidosis and Waldenström macroglobulinemia, has authored more than five hundred peer-reviewed publications, and is a master of the America College of Physicians. He graduated from Northwestern University with highest distinction as a Phi Beta Kappa and received his medical degree cum laude from Loyola Medical School and was elected to Alpha Omega Alpha, the medical honor society. He completed a three-year medical residency at Rush Presbyterian St. Luke’s Hospital in Chicago and was twice voted Resident of the Year.
