
Dr. Robert Z. Orlowski discusses immunotherapies, early smoldering myeloma treatment and clinical trials
Dr. Orlowski discusses his research and how faster progress could be made towards a cure if more patients participated in clinical trials. The interview covers four of the latest areas in myeloma research that Dr. Orlowski is pursuing: New treatment approaches where smoldering myeloma is treated earlier, Antibody treatments called PD-1 using a class of drugs already approved for melanoma, Two new immunotherapy approaches where the patient's immune system attacks the myeloma cells including a vaccine approach pre-transplant and also a way of purifying the gene that produces the abnormal protein that is then re-injected to try to stimulate an immune response. Dr. Orlowski also discussed a new class of drugs that prevent myeloma cells from making the protein Stat 3.
Dr. Orlowski discusses his research and how faster progress could be made towards a cure if more patients participated in clinical trials. The interview covers four of the latest areas in myeloma research that Dr. Orlowski is pursuing: New treatment approaches where smoldering myeloma is treated earlier, Antibody treatments called PD-1 using a class of drugs already approved for melanoma, Two new immunotherapy approaches where the patient's immune system attacks the myeloma cells including a vaccine approach pre-transplant and also a way of purifying the gene that produces the abnormal protein that is then re-injected to try to stimulate an immune response. Dr. Orlowski also discussed a new class of drugs that prevent myeloma cells from making the protein Stat 3.

Jennifer Ahlstrom

Robert Orlowski, MD, PhD