Hello Everyone, I have a double hit high risk MM with 17P deletion and 1Q amplification. I am going thru induction therapy, 2nd line, switched to Isa-KRD last 2 cycles. Before that I was on Isa-VRD for 4 cycles and developed severe eye sties. My STEM cell transplant is expected to take place around Fed 2024. When I started my induction my free light chain Kappas were around 1950 mg/L and M protein was at 2.3 g/dL. I got a really good response intially after being on Velcade for 2 cycles. My free light chain Kappas decreased to 436 mg/L and M protein went down to 1.7 g/dL. The numbers plateaued after that for 2 cycles. The numbers increased when I was put off of Velcade for a month. Since starting new regimen with Kyprolis, the numbers fluctuated in both direction intially but now my ight chain Kappas are at 222 mg/L and M protein wis at 1.0 g/dL. The M protein is at 1.0 g/dL for the last 5 weeks. I am reaching out to you all with 3 questions: 1. Does my numbers look like they are improving as expected? 2. What were your numbers before SCT? 3. Are these numbers expected to be normalize before SCT? Thank you so much for your time!

Cooling caps for ASCT with Melphalan. Success stories? There is currently a clinical trial at Cedars Sinai that is having 100% success with 0-30% hair loss. Saving 70% hair or more. I'm going to City of Hope and can use the cooling cap, but they won't allow the Penguin representative to help me. Only my caregiver.

Can someone tell me what BITE is like? I go in next week for a week at the hospital, getting dose escalation. Subcutaneous shots

I'm grateful to be in remission with MM since transplant 18 months ago and have been taking maintenance Revlimid for 15 months. Medicare Plan D carriers have mostly stopped covering name brand and I'm asking if any of you would share experience with generic lenalidomide. I used a generic in January and was sick for a month and lost 5 lbs, so I've been hesitant to try it again but I may have to. Thanks for any input you can offer.

Husband set to go this month for SCT outpatient. Timeline has been laid out for us and collection should start next week. 2 questions: he was told today that he need NOT be accompanied for collection line insertion on Monday but will need someone to go with him when it is removed. Should I go anyway? Also, he has completed 4 cycles of induction therapy with little interruption to daily activities. Since stopping his treatment medications a week ago in pregnancy for SCT, he really feels lousy for the first time p, especially at night. Is this normal? Thanks.