![[logo] HealthTree Foundation](https://static.healthtree.org/icons/icon_spinner.svg){kind=icon}
![[logo] HealthTree Foundation](https://static.healthtree.org/logo_icon_only.svg){kind=icon}
Mantle cell lymphoma (MCL) is staged using the Ann Arbor staging system, which is used for all types of lymphomas. This system classifies the disease into four stages based on the number of lymph nodes affected and the parts of the body involved.
Ann Arbor Staging System
The stages are as follows:
- Stage I: The cancer is found in a single lymph node region or in one organ outside the lymph nodes.
- Stage II: The cancer is found in two or more lymph node regions on the same side of the diaphragm, or the cancer has extended from a single lymph node region into a nearby organ.
- Stage III: The cancer is found in lymph node regions on both sides of the diaphragm.
- Stage IV: The cancer has spread widely into multiple organs outside the lymphatic system.
Each stage can also be classified as A or B. 'A' means the patient does not have symptoms such as fever, weight loss, or night sweats. 'B' means the patient has one or more of these symptoms.
Classification of Mantle Cell Lymphoma
Mantle cell lymphoma is classified based on its histological appearance, which can be either classic or variant. The classic form is characterized by a diffuse or nodular pattern of small to medium-sized lymphocytes. The variant forms include blastoid and pleomorphic, which are more aggressive and have a worse prognosis.
Classic and Variant Forms of Mantle Cell Lymphoma
The classic and variant forms are as follows:
- Classic Form: Characterized by a diffuse or nodular pattern of small to medium-sized lymphocytes.
- Blastoid Variant: Characterized by larger cells with more dispersed chromatin and prominent nucleoli.
- Pleomorphic Variant: Characterized by a mixture of small, medium, and large cells.
Phases of Mantle Cell Lymphoma
The phases of mantle cell lymphoma can be categorized into three main phases: the diagnostic phase, the treatment phase, and the follow-up phase.
Diagnostic Phase
This phase involves the identification of the disease through various tests such as physical examination, blood tests, imaging tests, and biopsy.
Treatment Phase
This phase involves the administration of treatment based on the stage and classification of the disease. Treatment options may include chemotherapy, immunotherapy, targeted therapy, stem cell transplant, or a combination of these.
Follow-up Phase
This phase involves regular check-ups to monitor the patient's response to treatment, manage side effects, and check for any signs of relapse.
Want to Learn More About Mantle Cell Lymphoma?
Keep reading HealthTree for Mantle Cell Lymphoma's 101 pages!
Mantle cell lymphoma (MCL) is staged using the Ann Arbor staging system, which is used for all types of lymphomas. This system classifies the disease into four stages based on the number of lymph nodes affected and the parts of the body involved.
Ann Arbor Staging System
The stages are as follows:
- Stage I: The cancer is found in a single lymph node region or in one organ outside the lymph nodes.
- Stage II: The cancer is found in two or more lymph node regions on the same side of the diaphragm, or the cancer has extended from a single lymph node region into a nearby organ.
- Stage III: The cancer is found in lymph node regions on both sides of the diaphragm.
- Stage IV: The cancer has spread widely into multiple organs outside the lymphatic system.
Each stage can also be classified as A or B. 'A' means the patient does not have symptoms such as fever, weight loss, or night sweats. 'B' means the patient has one or more of these symptoms.
Classification of Mantle Cell Lymphoma
Mantle cell lymphoma is classified based on its histological appearance, which can be either classic or variant. The classic form is characterized by a diffuse or nodular pattern of small to medium-sized lymphocytes. The variant forms include blastoid and pleomorphic, which are more aggressive and have a worse prognosis.
Classic and Variant Forms of Mantle Cell Lymphoma
The classic and variant forms are as follows:
- Classic Form: Characterized by a diffuse or nodular pattern of small to medium-sized lymphocytes.
- Blastoid Variant: Characterized by larger cells with more dispersed chromatin and prominent nucleoli.
- Pleomorphic Variant: Characterized by a mixture of small, medium, and large cells.
Phases of Mantle Cell Lymphoma
The phases of mantle cell lymphoma can be categorized into three main phases: the diagnostic phase, the treatment phase, and the follow-up phase.
Diagnostic Phase
This phase involves the identification of the disease through various tests such as physical examination, blood tests, imaging tests, and biopsy.
Treatment Phase
This phase involves the administration of treatment based on the stage and classification of the disease. Treatment options may include chemotherapy, immunotherapy, targeted therapy, stem cell transplant, or a combination of these.
Follow-up Phase
This phase involves regular check-ups to monitor the patient's response to treatment, manage side effects, and check for any signs of relapse.
Want to Learn More About Mantle Cell Lymphoma?
Keep reading HealthTree for Mantle Cell Lymphoma's 101 pages!
Get the latest thought leadership on your Mantle Cell Lymphoma delivered straight to your inbox
Subscribe to the weekly newsletter for news, stories, clinical trial updates, and helpful resources and events with cancer experts.
HealthTree Foundation is a qualified 501(c)(3) tax-exempt organization.
Copyright © 2024 HealthTree Foundation. All rights reserved.
Tax ID 45-5354811