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What is Chronic Neutrophilic Leukemia?

What is Chronic Neutrophilic Leukemia?

Chronic Neutrophilic Leukemia (CNL) is a rare myeloproliferative neoplasm characterized by a sustained, mature neutrophilic leukocytosis, splenomegaly, and a hypercellular bone marrow with granulocytic hyperplasia. It is a type of cancer that starts in the blood-forming cells of the bone marrow and leads to a high number of abnormal white blood cells (neutrophils) in the blood. CNL is typically slow-growing and is most often diagnosed in adults. The exact cause of CNL is unknown, but it is not a hereditary disease.

Why do people get Chronic Neutrophilic Leukemia?

The exact cause of Chronic Neutrophilic Leukemia is not known. However, it is believed to be associated with mutations in certain genes. In particular, a mutation in the colony-stimulating factor 3 receptor (CSF3R) gene has been identified in a significant number of people with CNL. This mutation leads to the overproduction of neutrophils, the white blood cells that fight infection. Despite this association, it is not clear why some people develop these mutations and others do not. It is important to note that CNL is not a hereditary disease and does not run in families. Other potential risk factors such as exposure to certain chemicals or radiation are also being studied, but no definitive links have been established yet.

Who gets Chronic Neutrophilic Leukemia?

According to the National Cancer Institute, there will be an estimated ___ new cases of Chronic Neutrophilic Leukemia in 2023, making up ___% of all new cancer diagnoses. In 2020, there were an estimated ___ people living with Chronic Neutrophilic Leukemia in the United States. (you get this info from the NCI’s SEER data. Add the link to this data as a hyperlink on the text “National Cancer Institute”

Want to Learn More About Chronic Neutrophilic Leukemia?

Keep reading HealthTree for Chronic Neutrophilic Leukemia's 101 pages!

What is Chronic Neutrophilic Leukemia?

Chronic Neutrophilic Leukemia (CNL) is a rare myeloproliferative neoplasm characterized by a sustained, mature neutrophilic leukocytosis, splenomegaly, and a hypercellular bone marrow with granulocytic hyperplasia. It is a type of cancer that starts in the blood-forming cells of the bone marrow and leads to a high number of abnormal white blood cells (neutrophils) in the blood. CNL is typically slow-growing and is most often diagnosed in adults. The exact cause of CNL is unknown, but it is not a hereditary disease.

Why do people get Chronic Neutrophilic Leukemia?

The exact cause of Chronic Neutrophilic Leukemia is not known. However, it is believed to be associated with mutations in certain genes. In particular, a mutation in the colony-stimulating factor 3 receptor (CSF3R) gene has been identified in a significant number of people with CNL. This mutation leads to the overproduction of neutrophils, the white blood cells that fight infection. Despite this association, it is not clear why some people develop these mutations and others do not. It is important to note that CNL is not a hereditary disease and does not run in families. Other potential risk factors such as exposure to certain chemicals or radiation are also being studied, but no definitive links have been established yet.

Who gets Chronic Neutrophilic Leukemia?

According to the National Cancer Institute, there will be an estimated ___ new cases of Chronic Neutrophilic Leukemia in 2023, making up ___% of all new cancer diagnoses. In 2020, there were an estimated ___ people living with Chronic Neutrophilic Leukemia in the United States. (you get this info from the NCI’s SEER data. Add the link to this data as a hyperlink on the text “National Cancer Institute”

Want to Learn More About Chronic Neutrophilic Leukemia?

Keep reading HealthTree for Chronic Neutrophilic Leukemia's 101 pages!

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