What are the common side effects of hypomyelopathy agents? What are the common side effects of hypomyelopathy agents? There's minimal side effect. Essentially, when we went to very low dose of the treatment compared to full dose as of the family of cytotherapy, we did not see the mild suppression. We do see with the high dose. So essentially, it's very well tolerated. Patient may experience some fatigue around day seven, eight, and nine, but very mild fatigue. And of course, we can have a drop of the count, but drop of the count is inherent to the disease by itself more than the drug. So I think these drugs are really quite safe to be given compared to intensive chemotherapy. And this is why they're really commonly used in a community setting without major problems. How are these side effects typically managed? How are the side effects typically managed of HMA? As I said, the side effect profile is very acceptable. I usually, when I have patients in my clinic, I explain to them what I'm giving to them, how the drugs works, why I do not expect side effect to be something of a major concern. I explain to them the fatigue may happen a few days, around day seven to day ten. So if you want to go for a big trip, try to avoid it. As communication always works with a patient. And then low count. In the low count, I advise them to get blood tests done weekly to see if the count is dropping, patient may need blood transfusion, platelet transfusion to be given. And of course, when the count is low and the patient with AML have a very weak immune system, they can have fever. Infection, I advise them to go to the hospital to be on antibiotic therapy. And on top of that, when the count is low, when I do blood tests weekly, I put them on prophylactic antibiotic, prophylactic antifungal therapy and antiviral therapy, so to avoid such complications.