When cells are being renewed on a daily basis,
in cancer, the hallmark of cancer is cells do not die.
In our normal body, so, you have your skin
that in the summer gets tan and then dies
and you have a new skin formed.
So there's a cycle of life.
Our cells are scheduled, are programmed in a way.
Our cells are scheduled, are programmed in a way.
They--they're born, they grow, and they die.
So cancer is: there no death of cells.
There's something called—that’s [what]
we call programmed death—apoptosis as a scientific term.
So there's inhibition of this processes
as such cells are living abnormally.
Essentially, they’re certain genes that are
being silenced, not functioning,
and therefore they have zero function against AML.
By removing the methyl group, CH3,
and then by expressing these genes,
the genes supposed to suppress
cancer are being active
and that is hypothetically supposed
to suppress development of cancer.
That's how it works.
So by removing the methyl group and expressing these genes,
we expect this gene to suppress the cancer.
And the cancer cells,
resume their normal cycle of life and go to die.
And therefore killing leukemia cells.
