Progress Toward an All Oral Treatment for Newly Diagnosed Older Adults with AML with Gabriel Mannis, MD
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Apple PodcastsGabriel Mannis, MD
Stanford Cancer Institute
Interview Date: September 13th, 2021
Dr. Gabriel Mannis of the Stanford Cancer Institute is studying what could become the first all oral therapy for older adults with newly diagnosed AML. The combination of venetoclax and decitabine with cedazuridine (a combination medication called ASTX727 or Inqovi) would provide older adults and those who cannot tolerate standard intensive chemotherapy a much needed alternative treatment option. Dr. Mannis shares details about how hypomethylating agents combined with venetoclax is an effective combination for older adults with AML and how oral therapies can give patients the freedom to live their lives without being confined to a hospital room. Medication options for older adults with AML are significantly advancing and becoming more effective. This exciting trial aims to add another treatment option to a patient's arsenal.
To learn more about the trial being discussed in today's episode,
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Gabriel Mannis, MD
Dr. Mannis is Assistant Professor of Medicine in the Division of Hematology at Stanford University School of Medicine, and Medical Director of Stanford’s Inpatient Leukemia Service. He specializes in the treatment of acute myeloid leukemia (AML), high-risk myelodysplastic syndromes (MDS), and other hematologic malignancies. As a clinical scientist, Dr. Mannis divides his time between caring for patients, teaching trainees, and researching novel therapies for AML and MDS.
Katie Braswell
Katie joined the HealthTree Foundation as the Community Director for AML in 2021. She is a registered dietitian who previously worked at the VA hospital in Dallas, Texas where she coached veterans with blood cancer on how to use nutrition to improve their treatment outcomes and minimize cancer-related side effects. Katie is passionate about health education and patient empowerment. In her spare time, she loves to experiment with new recipes in the kitchen, spend time running outdoors, and travel to new places.
