ABBV-383 is a unique bispecific antibody engineered to target both myeloma and T cells within the immune system. It is also unique as it is given intravenously (via IV) instead of subcutaneously (via injection). It's referred to as a BCMA x CD3 bispecific antibody. BCMA is the target that ABBV-383 uses to recognize multiple myeloma cells, and CD3 is used to recognize T-cells.
NCT05650632: Studying Adverse Events (like CRS) of Intravenously (IV) Infused ABBV-383
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Interview filmed at ASH in December 2023.