Can Resistance Exercise Help Heal Bone Lesions in Multiple Myeloma? | IMS 2026

Ulrike Dapunt, MD, of Heidelberg University Hospital discusses resistance training during induction therapy and bone healing at IMS 2026 in Glasgow. Most people with myeloma develop bone damage. In a 50-patient randomized study of supervised, home-based resistance training, patients who exercised lost less spinal bone density and showed more signs of lesion healing. Dr. Dapunt, an orthopedic and trauma surgeon, explains why getting an orthopedic consultation before starting is important because of injury risk.

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Timestamps:

0:00 Introduction: orthopedics for myeloma patients

0:47 Bone healing starts during induction therapy

1:34 Study design: 50 patients, home-based resistance training

2:10 Results: bone density and lesion healing

2:59 Did medications explain the results?

3:23 Takeaway: exercise early, with expert guidance