CAR-T GI Side Effects: Nausea, Diarrhea & Enterocolitis for Caregivers

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Nausea, vomiting, diarrhea, and changes in appetite can happen after CAR-T cell therapy. Most are temporary, but some patients develop more serious gastrointestinal complications. In this HealthTree video, we explain which GI side effects are common and when they occur, how to help manage diarrhea and prevent dehydration, and when diarrhea may signal immune effector cell-associated enterocolitis, a rare complication seen after some BCMA-directed CAR-T therapies for myeloma. You'll also learn when to contact the care team.

Part of HealthTree University's Caring with Confidence: A Practical Guide for CAR-T Caregivers course.

Timestamps:

0:00 Introduction

0:28 Common GI side effects and when they occur

1:45 Managing diarrhea after CAR-T

3:02 Preventing dehydration

4:33 Immune effector cell-associated enterocolitis

6:01 How serious it can get and when to call

This video is for educational purposes only and is not medical advice. Always follow your CAR-T care team's instructions.

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