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Video

Guest Lecture - CAR-T Side Effects in Myeloma: Understanding IEC-EC for Healthcare Providers and Patients

Posted by
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• September 17, 2026

Description

What is IEC-EC after CAR-T therapy, and how can patients and healthcare providers recognize it?

In this fireside chat, Dr. Samir Parekh and Dr. Mehandru, a gastroenterology specialist at Mount Sinai, discuss the latest research on immune effector cell–associated enterocolitis (IEC-EC), an emerging gastrointestinal complication that can occur after CAR-T therapy.

They explain what is currently known about CAR-T–related diarrhea, abdominal pain, cramping, fever, and blood or mucus in the stool, as well as how IEC-EC may be distinguished from infection, medication side effects, or other causes of gastrointestinal symptoms.

Because IEC-EC is a new and rapidly evolving area of CAR-T care, this discussion reviews current approaches to diagnosis, timing, treatment, and multidisciplinary management, including when gastroenterology specialists may become involved.

This video is designed for both patients and healthcare providers and is especially relevant to people receiving CAR-T therapy for multiple myeloma and the clinical teams caring for them.Topics include:

What IEC-EC is

Symptoms of IEC-EC after CAR-T

CAR-T–related diarrhea and enterocolitis

How IEC-EC is diagnosed

How doctors rule out infection

Current treatment approaches

The role of gastroenterology

Emerging research in IEC-EC

What patients should report to their care team