Are there myeloma patients here that experience a progression of bone disease even though you are in remission? I experienced compression fractures in my spine because of MM damage and in the first year of treatment for the cancer, those fractures healed pretty well. I've been in remission for most the past ten years. However, through the last several years, I notice that my spine hurts whenever I rise up from a lying position. Years ago, it was only a mild pain that lasted less than a minute, then went away without problems. But in the last several months, the pain has gotten much worse - around 7 - 8 on a 1 - 10 scale - and it lasts for many minutes. I've read that myeloma can cause permanent changes to bone chemistry that causes continued damage even without the presence of cancer cells, and I fear that's what I'm experiencing now. My doctors haven't explained much of this to me and I've decided to find out as much as I can about this and what the prognosis is. So I wonder how common this kind of bone pain is among MM patients and would appreciate any input from others. Thanks.