After 12 weeks of drug treatment, I reached remission. My case was stage 1. While I successfully reached remission, I now have a blazing case of peripheral neuropathy. Feet are on fire, sleep is difficult, and 4 fingers are cold and restrictive inn use. The culprit in this is Velcade. Anyone taking drug treatment should be aware of this. I am convinced that reduced doses of Velcade would be preferable to the terrible neuropathy I now suffer. LEN PAULSEN Brentwood TN