Has anyone with multiple myeloma experienced jaw pain while on denosumab? I have multiple myeloma and have been receiving denosumab every three months. Over the past six months, I underwent two dental implant procedures in my upper jaw. Unfortunately, I developed severe jaw pain after the implants, prompting their removal. While the pain has improved, it persists in a milder form in the lower jaw. A PET-CT scan showed no structural bone damage in the jaw, only inflammation. Could this pain be related to an infection from the implants, or is it more likely osteoarthritis or osteonecrosis? Could the denosumab be a contributing factor? If so, would discontinuing denosumab help alleviate the pain or is it a permanent issue? Thank you very much, grateful to have access to this community!