After diagnosis 4/9/21 at 75, I started on Dara/Rev/Dex. My M-spike, light chains and all other lab values gradually shifted into the normal ranges. In May of 2023, with my M-spike at zero, we decided to stop the Rev, Dex and daily aspirin (continuing the monthly Darzalex Faspro injections). Since that time my M-Spike has slowly increased to .37 as of 1/17/2025 (light chains in normal range). My oncologist has suggested going back on Rev or maybe Pomalyst, (we’re waiting a couple of months to see what happens). **Update 07/24/2025** My M-Spike is gradually rising now up to .53. We have decided to add Pomalyst 21/7 and Dexamethasone once a week. I hate to do it, but the idea is to catch it before it runs away. Back to the brain fog, constipation, fatigue and bruising, oh well it is what it is, have to deal with it. I was on Revlimid originally, does anybody know if there are differences in side effects with the Pomalyst.