Has anyone experienced bad skin rash around the Velcade injection spot and elsewhere on the body ? If yes how did you manage ? I am on quadruplets induction therapy second month and I am experiencing pretty bad skin rash with Velcade. 1st month it went all over the abdomen and even under the armpits. We had to stop Velcade for 4 weeks … Second month - We slowed the injection pace and it helped contain the rash around the injection spot. Still after the 4th jab the skin rash has again migrated to the armpits… My haematologist was suggesting intravenous injection instead of subcutaneous… Would appreciate any feedback. Update - I now have done 2 - IV Velcade injection and so far all good 👍🏽. No skin rash .