I was diagnosed in Nov 2021, IgG Lambda MM. I have t(4,14). I have been MRD negative or quite close to that since June 2022, when i had my ASCT. I took Revlimid 10 mg and Velcade 1 mg as maintenance beginning in Sept 2022. At the two year mark after my ASCT, in June 2024, I was taken of Revlimid, and my Velcade dose was reduced from 1 mg to .7 mg. I get Velcade every two weeks and for the past three months it has made me very sick and I throw up the night after I get the shot and I am really nauseous for about a week after I get the shot. My phosphorous, LDH and other kidney indicators were very high today and I am concerned that that the meds are hurting my kidneys (my protein numbers seem to indicate that I am still in remission). Does anyone ever just take the week off of chemo? I am interested only in people who have considered skipping a treatment and have made a decision one way or another. To be clear - I like my doctor and follow his advice to a t. I just feel that my LDH, phosphorous and other numbers seem to indicate that my organs are suffering more than my cancer is right now and should I take a week off to try to give my kidneys a break? I am not seeking advice, but I'm interested in experiences, and I'm grateful for them. I listen to my doctor. I am interested in hearing about others' experience. Thank you for your thoughts and experiences.