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Ligeross@3000
Multiple Myeloma Discussion • February 28, 2024
Sharing My 20-Year Journey & Hope for Future Research
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I was diagnosed with stage 3a mm in 2004 at age 45. I researched the best available treatments and learned that double or tandem transplants gave the best long term results. I went to the UAMS MIRT center in Little Rock, Arkansas and got on their TT3 clinical trial which offered tandem transplants. I went into complete remission for 14 years. In December 2022 I received Car T Carvykti and have been in remission since. I continue to look at the latest mm research. Bispecific antibodies are promising, but the best research I can find in 2024 is CAR T CD 229 which kills plasma cells AND the mm stem cells. Killing the mm stem cells in theory should produce long term remission and possibly a cure because these stem cells are what regrow the cancer. CAR T CD 229 is preclinical at Johns Hopkins in Baltimore, MD, but they are planning to do clinical trials. If CAR T CD229 becomes available for me in the future, THAT is the treatment I will want because of its potential “cure” by killing the mm stem cells. For now, bispecific antibodies and the latest drugs available are what is out there. What I recommend is to get on one of these latest treatments or clinical trials and keep up with the research. I await the start of the CAR T CD 229 trials.
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