I was diagnosed with IGA multiple myeloma four and a half years ago. I completed, 16 weeks chemotherapy and then completed a successful stem cell transplant. Following my 100th day testing showed complete remission. Remission lasted until last May when a solitary plasmacytoma was detected in my upper humerus bone. A PET scan showed the tumor very clearly. But no other site involved . Following radiation I started daralex faspro. An additional PET just before surgery showed multiple lytic lesions throughout my body. Surgery was suggested because of damage to the bone and worry of fracture. I had a complete reverse shoulder replacement in November. Following surgery Velcade and dexamethasone were added to the chemotherapy. These were to work to reduce the lesions. They seem to be working but on a lumbar vertebrae it not recovering as one would hope. So we continue chemotherapy and will be back to radiation on the vertebrae. The hope is to get back to remission. Does anyone have experience with IGA? It's the second most common but a little more aggressive than IGG. Thanks for any experience you can share.