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tim_brinker@sbcglobal.net
Multiple Myeloma Discussion • January 8, 2025
CAR-T After Blenrep & Plasmacytomas: Experiences?
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Hi Myeloma Warriors - Tim here a 14 year myeloma survivor. I have been through a myriad of therapies. One of my longest lasting therapies was Balatamab (Blenrep). I was on Blenrep for 3 1/2 years until my ophthalmologist didn’t approve me to continue, that was March 2024. I have been on no treatment since then, basically waiting for my bloodwork to show active myeloma. In November I started having numbness in my lower back, an MRI identified this as a plasmacytoma in my sacral. I had five days of radiation and began to prepare for CarT. Between November and now another plasmacytoma appeared on my skull, causing headaches and spots have developed on my gallbladder (found on a CT scan last week, had MRI yesterday to further analyze). I start t-cell depletion tomorrow and will receive my T-Cells back next week. I have a few questions: 1. Anyone have success with CarT after being on Blenrep. Now I didn’t fail Blenrep, Blenrep was stopped because of eye impacts. 2. Anyone have success with CarT and plasmacytoma’s and/or extramulldury disease? Thanks, Tim
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